Cholesterol and Triglycerides May Reached the Undesirable Level in Gestational Diabetes Mellitus

Abstract

4 Abstract: Lipid profile including cholesterol, triglycerides, High Density Lipoprotein-cholesterol (HDL-C) and Low Density Lipoprotein-cholesterol (LDL-C) level was determined in patients with Gestational Diabetes Mellitus (GDM) and compared to Healthy Pregnant Women (HPW). 103 GDM women and 97 HPW were registered in the Khyber Teaching Hospital, Peshawar in the time period of May to December 2012. Total cholesterol, triglycerides, HDL-C and LDL-C was determined by standard kit procedures. Mean Total Cholesterol (TC) and mean Triglyceride (TG) were significantly higher at P<0.05 in GDM group as compared to HPW group. The mean value of total cholesterol in GDM group was 205.81±19.09 mg/dL while in HPW (control group) it was 194.86±23.70 mg/dL. The mean TG level of GDM women was 189.62±20.01 mg/dL while of HPW was 169±22.26 mg/dL. The mean HDL cholesterol (HDL-C) and the mean LDL cholesterol (LDL-C) of GDM women were non significantly higher than HPW. The percentage of GDM in undesirable level of cholesterol (P = 0.03) and triglycerides (P = 0.003) was significantly higher as compared to HPW, however the percentage of GDM in undesirable level of HDL-C and LDL-C was non significantly different from HPW.