Abstract
：Objective To analyze theexpression of cholecystokinin(CCK) in rat' s hippocampus and cerebral cortex followingheat stress and febrile convulsions (FC). Methods Warm water was used to induce FC model.Immunohistochemistry method tested CCK protein. Results Very few or no CCK neurons wereseen in the control rats. There was weaker expression of CCK in cerebral cortex of HSgroup,mainly located in PIR,ENT and RS subfield.No CCK positive ceiis were seen inhippocampus of HS rats. In contrast, abundant expression of CCK protein was found inhippocampus and cerebral cortex of FC group. They were well-distributed, withoutcharacteristic subnucleus-specific distribution. Conclusion Abundant induction of CCK inhippocampus and cerebral cortex of FC group suggested that CCK may play a role in thecentral control of FC.
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