Chitosan Nanoparticles Functionalized Viscose Fabrics as Potentially Durable Antibacterial Medical Textiles.

Matea Korica,Tanja Nikolić,Snežana Trifunović,Mirjana M Kostić,Alenka Vesel,Katarina Mihajlovski,Zdenka Peršin,Biljana Dojčinović,Lidija Fras Zemljič

doi:10.3390/ma14133762

Abstract

This research proposed two pretreatments of viscose fabrics: oxidation with 2,2,6,6-tetramethylpiperidine-1-oxy radical (TEMPO) and coating with TEMPO-oxidized cellulose nanofibrils (TOCN), to introduce functional groups (COOH and CHO) suitable for irreversible binding of chitosan nanoparticles without and with embedded zinc (NCS and NCS + Zn, respectively) and consequently achieving washing durable antibacterial properties of the chitosan nanoparticles functionalized fabrics. The characterizations of pretreated and chitosan nanoparticles functionalized fabrics were performed by FTIR and XPS spectroscopy, elemental analysis, inductively coupled plasma optical emission spectrometry, zeta potential measurements, scanning electron microscopy, determination of COOH and CHO groups content, and antimicrobial activity under dynamic contact conditions. Influence of pretreatments on NCS and NCS + Zn adsorption, chemical, electrokinetic, and antibacterial properties as well as morphology, and washing durability of NCS and NCS + Zn functionalized fabrics were studied and compared. Washing durability was evaluated through changes in the chitosan and zinc content, zeta potential, and antibacterial activity after 1, 3, and 5 washing cycles. Pretreatments improved washing durability of antibacterial properties of chitosan nanoparticles functionalized fabrics. The NCS and NCS + Zn functionalized pretreated fabrics preserved antibacterial activity against S. aureus after five washing cycles, while antibacterial activity against E. coli was preserved only after one washing cycle in the case NCS + Zn functionalized pretreated viscose fabrics.

Highlights

IntroductionThe molecular structure of viscose offers numerous possibilities for the development of a broad spectrum of medical textiles with special properties such as, for example, antibacterial [2,3,4,5]
The Fourier transform infrared (FTIR)-ATR spectra recorded to characterize the surface of pristine, pretreated, NCS and NCS + Zn functionalized viscose fabrics include characteristic bands of cellulose (Figure 1): at 892–896 cm−1 is the band corresponding to C–O–C valence vibration of β-glycosidic linkage or C1-H deformation in cellulose II; at 996 cm−1 is the band related to
C–O valence vibration at C6; the band at 1024 cm−1 is characteristic for C–O stretching; the band at 1067 cm−1 corresponds to C–O vibration mainly from C3–O3H in cellulose II; the band at 1158 cm−1 is related to C–O–C asymmetric valence vibration from β-glycosidic linkage in cellulose II; the bands at 1200 and 1336 cm−1 originate from OH in-plane deformation; the band at 1225–1235 cm−1 is due to O–H in-plain deformation at C6; the band at 1316 cm−1 is related to CH2 wagging vibration; the band at 1372 cm−1 is due to

Summary

Introduction

The molecular structure of viscose offers numerous possibilities for the development of a broad spectrum of medical textiles with special properties such as, for example, antibacterial [2,3,4,5]. Used compounds for antibacterial functionalization of medical textiles are antibiotics such as quinolones [6], 4.0/). The use of antibiotics for the antibacterial functionalization of medical textiles is not recommended due to the increasing development of antimicrobial tolerance and resistance [11]. Uncommon, non-antibiotic antibacterial agents, such as chitosan and metals, are included in novel strategies for the development of a novel generation of antibacterial medical textiles based on viscose [5,12,13,14,15,16]

Methods

Results

Conclusion