ChemInform Abstract: One‐Pot Stereoselective Synthesis of (Z)‐α‐Arylthio‐α,β‐unsaturated Ketones by Hydrostannylation—Stille Tandem Reaction of Acetylenic Sulfides.

Abstract

(Z)-α-Arylthio-α,β-unsaturated ketones can be stereoselectively synthesized in one pot under mild conditions, in good yields, by the palladium-catalyzed hydrostannylation of acetylenic sulfides with tributyltin hydride, followed by Stille coupling with acyl chlorides.