A One-Pot, Stereoselective Synthesis of (Z)-1,2-disubstituted Vinyl Sulfides by Sequential Hydrostannylation and Stille reaction of Acetylenic Sulfides with Tributyltin Hydride and then with aryl iodides

Abstract

( Z)-1,2-Disubstituted vinyl sulfides can be stereoselectively synthesised in one pot under mild conditions, in good yields, by the palladium-catalysed hydrostannylation of acetylenic sulfides, followed by Stille coupling with aryl iodides.