ChemInform Abstract: Nickel(II)‐Catalyzed Asymmetric Michael Addition of Oxindoles with Modified N,N,O‐Tridentate Chiral Phenanthroline Ligands.

Abstract

Nickel(II)-catalyzed enantioselective Michael addition of N-Boc-oxindole derivatives with methyl vinyl ketone was demonstrated to give the corresponding adducts having chiral all-carbon quaternary centers with up to 87% ee in the presence of axially chiral N,N,O-tridentate phenanthroline ligand.