ChemInform Abstract: Enantioselective Construction of Quaternary Stereogenic Carbon Atoms by the Lewis Base Catalyzed Additions of Silyl Ketene Imines to Aldehydes.

Abstract

AbstractThe presented reaction gives alcohols bearing quaternary stereocenters in high yields and excellent diastereo‐ and enantioselectivities tolerating a broad scope of aliphatic and aromatic substituents on both, the aldehyde and ketene imine.