ChemInform Abstract: Copper‐Catalyzed Direct C—H Arylation of Pyridine N‐Oxides with Arylboronic Esters: One‐Pot Synthesis of 2‐Arylpyridines.

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The first example of the copper-catalyzed direct C–H arylation of pyridine N-oxides with arylboronic esters has been developed, leading to a wide range of 2-arylpyridines in a one-pot synthesis with moderate to good yields without an additional reductant. This transformation allows for rapid access to a variety of 2-arylpyridines using an inexpensive catalytic system that would be more difficult to access with traditional methods. Thus, this method represents a simple and practical procedure to access 2-arylpyridines.