Abstract
Abstract We report a practical and highly efficient protocol for the arylation of pyridine N -oxides with arylboronic acid through palladium-catalyzed Suzuki reaction in water. This ligand-free Suzuki reaction is performed in the presence of diisopropylamine and gives 2- or 3-arylated pyridyl N -oxide derivatives in good to excellent yields within 1 h.
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Schedule a callMore From: Chinese chemical letters = Zhongguo hua xue kuai bao
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