Abstract
Stability constants of metal chelates of dicyclomine hydrochloride (dcm), metformin hydrochloride (mfm) drugs with the Co II , Ni II and CU II transition metal ions have been evaluated pH metrically in aqueous solution at 25 C and 0.1 M (NaClO 4 ) fixed ionic strength. Proton ligand stability constant and metal ligand stability constant were determined by Calvin-Bjerrum pH titration techniques as modified by Irving and Rossotti.
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