Abstract
Objective: The objective of the study was to establish potential uses of the fruit peel and seeds from Passiflora vitifolia collected in the Colombian Central Andes.
 Methods: The physical characteristics and chemical profile of the byproducts were determined. The ethanolic extracts of these materials were used to assess the content and phytophenols composition, to establish the antioxidant potential and the antidiabetic activity, in vitro inhibition of α-amylase enzyme and glucose diffusion. The performance and physicochemical composition of the seed oil was also evaluated.
 Results: The seeds contain almost 4 times more phenolic compounds (10 671 mg GAE/100 g sample) than the peel (2817 mg GAE/100 g sample). Likewise, crude protein and fat contents from the seeds are higher (15.5% and 25.6%) than the peel (6.60% and 5.70%, respectively). Nine phytoconstituents were positive for both extracts. Significant variation (p<0.05) of antioxidant and anti-hyperglycemic potential was observed among the peel and seeds in all methods applied.
 Conclusion: Results showed that the byproducts of P. vitifolia fruit could be used to enhance the nutritional quality of functional products. These findings were also confirmed by the ethanolic extract from seeds, which revealed high levels of phenolics, high antioxidant potential, and anti-hyperglycemic activity that make it a promising phytotherapeutic product, all of which gives added value to the fruit of this wild Passiflora.
Highlights
According to the Alexander von Humboldt Biological Resources Research Institute, Colombia has approximately 170 Passiflora species, among which 45 are exclusive of the Andean region
The texture value of P. vitifolia fruit (17.80±0.08 N) would be associated with the thickness of the peel (58.00±1.08 mm), which is higher compared to hardness and thickness values found in other species of the genus [26]
The exploratory evaluation of physicochemical parameters and nutritional composition of residual biomass, such as P. vitifolia peel and seed, can be a viable economic alternative because it adds value to the plant product as a source of bioactive compounds. This supports the idea of proposing the fruit byproducts of P. vitifolia, an unconventional passionflower, in animal feed and suggests its potential use as a promising product
Summary
According to the Alexander von Humboldt Biological Resources Research Institute, Colombia has approximately 170 Passiflora species, among which 45 are exclusive of the Andean region. Some of them are prominent for internal consumption and with export potential [1] Despite these facts, the literature survey has revealed that several fruits are not available in our market, many others remain anonymous and very little work has been done on wild passionflower species, as in the case of Passiflora vitifolia (granadilla de monte or güillita). The literature survey has revealed that several fruits are not available in our market, many others remain anonymous and very little work has been done on wild passionflower species, as in the case of Passiflora vitifolia (granadilla de monte or güillita) It is one of the more than 530 species that form Passiflora genus (Passifloraceae), distributed mainly in the New World [2]. It is found with a lower frequency in Australia, Africa, or Asia [3]
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