Abstract
To compare fibroplasia and the resistance of the abdominal wall when polypropylene meshes and polypropylene/poliglecaprone are used. Seventy-seven male Wistar rats were divided into three groups: Control Group (for resistance); Group E (polypropylene mesh); and Group U (polypropylene/poliglecaprone mesh). The animals in Groups E and U had a standard muscular and aponeurotic defect, with integral peritoneum, and correction with the mesh. Measurements were taken 4, 7, 14, 28 and 56 days after surgery. The resistance, and collagen density were studied. Resistance on the 56th day was similar in both meshes. The gain in resistance described an ascending curve for the polypropylene mesh and was irregular in the case of the polypropylene/poliglecaprone. Fibroplasia showed a gain in type I and type III collagen in both groups (p<0.001). Collagen III stabilized in the 14th day and collagen I continued to ascend. The gain in resistance of the polypropylene mesh is regular and ascending, whereas the polypropylene/poliglecaprone is not regular. The final resistance of both meshes is similar; the collagen density increases over time, and show the same inflammatory potential.
Highlights
Ventral hernia or eventration consists of protruding viscera through an abnormal opening in the abdominal wall following a surgical procedure[1]
This is a result of atrophy, fatty degeneration and fibrosis of the lateral muscles, factors that hinder the reinsertion of the reinsertion of the tendon in the supporting muscle[8]
The study was evaluated by the Ethics Committee on the Use of Animals in Biological Sciences, Universidade Federal do Paraná (UFPR), allotted process number 23075.038578/201211, approved on 30/11/2012 - R.O. 11/2012, as number 659 and in compliance with Federal Law 11.794, which establishes the procedures for the scientific use of animals
Summary
Ventral hernia or eventration consists of protruding viscera through an abnormal opening in the abdominal wall following a surgical procedure[1].According to an American analysis, one in ten patients submitted to a laparotomy develops an incisional hernia[2,3,4]. Ventral hernia or eventration consists of protruding viscera through an abnormal opening in the abdominal wall following a surgical procedure[1]. An incisional hernia forms due to defective healing following a laparotomy, the mechanism of which is of a multi factor nature. When the insertion of the tendon is dislocated from the large muscles that support the abdomen and their retraction, incisional hernias worsen, especially those of the median line. This is a result of atrophy, fatty degeneration and fibrosis of the lateral muscles, factors that hinder the reinsertion of the reinsertion of the tendon in the supporting muscle[8]
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