Abstract
Sheet methods—such as paper and thin-layer chromatography—are used to separate a wide variety of organic and inorganic mixtures. A sheet method is considered an open, thin column. This technique, in comparison to column techniques, has the advantages of being simple, rapid, and inexpensive. It also provides excellent resolving power. Although quantitative results are possible, the main application is in qualitative identification, because very small quantities of sample are easily handled. Sheet methods can also be scaled up to handle purification on a preparative basis. Because a sheet method is similar to a column method, adsorption, partition, sieving, and ion exchange are readily carried out on a sheet. Inorganic as well as organic mixtures are separated by sheet methods. The chapter also describes the experimental procedures, which include pretreatment, sample application, developing chambers, development, and visualization.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call