Abstract

Neuronal tumors are the rare neoplasms that contain both neural and glial components and have WHO grade I clinical behavior. They are commonly found in the population of children and young adults. Neuronal and mixed neuroglial tumor subtypes are still being defined, although they include central neurocytoma and its variants, gangliocytoma, dysplastic cerebellar gangliocytoma, ganglioglioma, desmoplastic infantile astrocytoma, dysembryoplastic neuroepithelial tumor, and anaplastic ganglioglioma. They look differently on radiographs, with some having huge heterogeneous solid/cystic masses so their classification is still evolving as the large-scale genetic and molecular research is going on. The present chapter is intended to highlight the basic understanding of the cellular, molecular mechanism and the genetic alterations which can lead to the development of neuronal tumors based on the current literature that may also be useful for scientific community.

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