Abstract
Strains of Lactobacillus casei and Lactobacillus paracasei are widely utilized as probiotic or synbiotic supplementations to improve clinical outcomes. Here, the results from a number of clinical trials that have assessed the efficacy of these probiotic strains are summarized. These trials include quantitative evaluation of the influences of L. casei and L. paracasei on patients with conditions ranging from a variety of digestive diseases, chronic infectious diseases, obesity, and depression disorders. For each trial, the major findings are documented, as well as a comparison of clinical trials that yield conflicting conclusions. Finally, recommendations for the future assessment of probiotic functions will be stated.
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