Abstract

Our understanding of diseases and disorders is nowhere close to the finish line; in fact it has just begun. The threat of new infections and emergence of antibiotic-resistant microbes has kept the scientific community on its toes. However, from the early days of molecular biology to the current era of genomics, the global model of diagnosis, control, prevention, and treatment is changing rapidly. The availability of highly sensitive and specific diagnostic techniques such as high-resolution single nucleotide polymorphism–level tracking of disease spread and transmission, accurate molecular epidemiology of pathogens; reverse genomics–based vaccines for prevention, and modern genomics-based therapeutics have only become possible because of introduction of translational “-omics” in today's commercial and academic research and development.

Full Text
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