Abstract
Today, osseointegration is the attractive topic or concept for the development of the orthopedic implants. It has been found that mechanical integration of the implant to the bone would not be effectively sufficient for the long-term stability of the implant when implanted into the bone. It was extensively addressed that biological interaction between the bone and the implant would enhance early and long-term integration of the bone and the implant, which has significantly improved the treatment of bone injury. In this chapter, the general concepts that are currently considered as development strategies for the fabrication of the orthopedic implants are addressed and their importance would be then expressed. Likewise, the engineering and processing challenges or aspects of the osseointegration that manufactures deal with are discussed. One of the important topics in the development of the orthopedic implants with osseointegrity characteristics is the evaluation methods that could validate the effectiveness of osseointegration after implantation. This topic would be elaborated in this chapter. Finally, several clinical and surgical aspects of the osseointegration are reviewed from which the clinical concerns that might be contemplated in the development of osseointegration are clarified.
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