Abstract

As the prevalence of peripheral artery disease continues to increase, the open treatment of infrainguinal peripheral artery disease remains an essential option. There are many important factors to consider when evaluating female patients for bypass, including artery diameter, diseases burden, conduit size, timing of presentation, and hormonal factors. However, despite advances in medical therapy and surgical technique, many conflicting reports exist regarding outcomes in women, with more recent, large database studies demonstrating that women have lower patency and limb salvage rates and increased mortality rates. This chapter examines these factors because they relate to open surgical infrainguinal treatments in women and the effects of sex on outcome.

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