Abstract

A diagnosis of thoracic aortic dissection should be considered in any patient presenting with chest pain. Thoracic aortic dissection is relatively rare but when undiagnosed, often portends to poor prognosis. Owing to relatively small numbers of patients presenting with aortic dissection, the International Registry of Acute Aortic Dissection was established to better understand aortic dissection pathophysiology, clinical presentation, and, in turn, treatment options. The registry has more recently evaluated differences of clinical presentations, management in outcomes, between sexes. In-hospital complications have occurred with greater frequency in women than men, resulting in higher in-hospital mortality. What causes this disparity? Women tend to have a longer life-expectancy than men. Should this gap affect the criteria in which uncomplicated Type B aortic dissections are treated in women? Women tend to have smaller access vessels and greater angulation of the aortic arch. Should this difference tailor treatment options?

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