Abstract
Multiple sequence alignments are a necessary part of protein structure and function prediction, phylogenetic inference and a wide range of other useful procedures in sequence research. Multi-sequence alignment is one of the oldest computational biology issue. It has more than two DNA, RNA or protein sequences that are associated with it. One frequently employed technique is to eliminate misplaces, inserts and deletions in the alignments, and an optimal alignment can be calculated using the Dynamic Programming algorithm. This chapter includes the most commonly used multiple sequence alignment softwares and tools.
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