Chapter 6 - Pathology of Primary Brain Tumors—Gliomas

Abstract

Integrative diagnosis of glioma encompassing clinically relevant molecular biomarkers with traditional “glass-based” or “analog” descriptive diagnosis represents the next generation of oncologic neuropathology. This provides the most direct and clinically informative information to aid in the clinical management of patients with infiltrative glioma. This chapter will cover the revised diagnostic entities brought forth in the 2016 WHO Classification of Tumours of the Central Nervous System with particular focus on low-grade gliomas and glioblastomas.