Abstract
Biotoxins pose a serious threat to human health because of their high toxicity and harmfulness. Seeking rapid and sensitive analysis methods is an important way to prevent food poisoning caused by biotoxins. A new recognition molecule known as an aptamer that was obtained by systematic evolution of ligands by exponential enrichment (SELEX) in vitro has attracted much interest. It possesses great affinity and specificity. The corresponding construction of aptasensor with excellent performance has been promoted by the rapid development of molecular biology, chemistry, and materials science and has been broadly utilized in the analysis of biotoxins. In this chapter, the progress of aptamers and aptasensors utilized for biotoxin analysis in food samples in recent years was summarized, and the challenges and opportunities were discussed. We hope this chapter can provide a reference for future research and promote the development of innovative methods of aptamer screening and aptasensor construction.
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