Abstract
Polyphenols are among the most abundant and beneficial antioxidants in nature. This review examines the virtues of various polyphenols and recommends quercetin dihydrate flavonoid and soluble orthoproanthocyanidin (OPC) flavanol, with or without ellagic acid, as the dream team that supports safer, and more effective, protection from free radical damage. The discussion includes tests of antioxidant potency such as ORAC and surveys the research evidence on functional benefits of these nutrients. Key predictive biomarkers are reviewed that can be used as valuable tools in clinical assessment of risk and resilience. Biochemical individuality supports supplement use in physiologically meaningful amounts for each individual, monitored through predictive biomarker lab tests to determine individual need. Predictive biomarker tests are more helpful when interpreted or referenced to best outcome goal values.
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