Abstract

Poliovirus (PV) belonging to the Picornavirus genus, Picornaviridae family, is ribonucleic acid (RNA) virus, the leading cause of neurological diseases and disability in developing countries. New infections typically attributed to emerging and reemerging RNA viruses that have expanded their geographic range contributing to the burden of disease. This is what prompted the World Health Assembly in 1988 to adopt the goal of global polio eradication through intensive use of the trivalent oral polio vaccine (OPV). Wild PVs (WPVs) became endemic in only four countries.

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