Abstract
Magnetoencephalography recordings (MEG) are a useful tool in basic brain research and are likely to be suitable for clinical applications. As the patients are not subjected to radioactive traces, X-rays, or powerful magnetic fields, and thus the measurements are truly non-invasive. In addition, MEG recordings are fast and easy to perform. With MEG, it is possible to combine excellent temporal resolution with reasonably well spatial resolution, because MEG, like electroencephalography (EEG), measures electromagnetic signals of the brain activity directly instead of activity related changes in metabolism or blood flow. On the other hand, MEG measurements usually require a magnetically shielded environment and well-trained personnel to take care of measurements and analyses of the data. In MEG recordings, the data has to be modeled to achieve accurate localization of active brain areas. MEG has two important clinical applications that are already available—localization of the epileptogenic cortex with respect to functional landmarks and functionally important cortical areas and preoperative localization of functionally important cortical areas in brain tumor patients. The experiences of MEG recordings in preoperative patient evaluation, localization of epileptogenic foci, and in motor and language disorders are described in this chapter.
Published Version
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