Chapter 4 - A brief study of genes vital for diabetes and their relationship

Abstract

Occurrence of noncommunicable diseases (NCDs) is showing exponential increase at an alarming rate across the world. Both developing as well as developed countries are experiencing similar situation. India is projected to become global capital of diabetes in near future. Thus better understanding of this disease requires extensive study of interplay between all the underlying components. The following study was carried out with the aim of identification of relationship between genes related to this disease and their effect on its onset and progression. For this purpose, most important genes as well as frequency of reported genes relevant to diabetes were identified from secondary data available through various websites and online resources. Proteins encoded by the important genes linked with diabetes were subsequently found. Gene–gene interactions/gene–protein interactions with respect to some of these genes were further identified which ultimately led to the map of interacting genes/effected genes/proteins.