Abstract
Morus nigra is commonly known as black mulberry and is used medicinally for its anti-inflammatory and antioxidant property. Little attention has been given toward its neuroprotective efficacy. Among various neurodegenerative disorders, Parkinson's disease (PD) is a common neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra of the midbrain. Oxidative stress in substantia nigra due to the deposition of α-synuclein in the form of Lewy bodies (LBs) is also considered to be an important factor in the progression of PD. A number of natural plant products/extracts have been reported to be neuroprotective against PD symptoms. The treatment with conventional drug is associated with side effects; hence, there has been an increase in interest toward the traditional medicines mainly herbal medicines. In the present chapter, we have discussed PD and the studies carried out on the M. nigra for the neuroprotection against PD.
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