Abstract
Blood loss resulting from vascular injury is mitigated by hemostasis, separated into primary (platelet-based) and secondary (coagulation cascade-based). The coagulation cascade is comprised of intrinsic, extrinsic, and common pathways made up of various factors that act in tandem to prevent hemorrhage. The activated partial thromboplastin time (aPTT) measures activity in the intrinsic cascade, while prothrombin time (PT) measures the extrinsic cascade. Abnormalities in these coagulation studies can be traced back to the cascade factors themselves, including factor deficiencies or inhibitors; mixing studies can confirm the etiology of the abnormal coagulation study.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
