Abstract
Discovery of proteomic (proteome) biomarkers is helpful for early tumor diagnosis, prognosis, and treatment. Proteins present in blood released from diseased cells and surrounding tissues contain important biological information with the potential to transform early diagnostic, prognostic, therapeutic, and even preventative decisions in medicine. This chapter reviews the bioinformatics methods for proteomics biomarker discovery with related issues and the improved knowledge-based network biomarkers.
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