Abstract
Wearable biomonitoring technologies provide insight into the body’s physiological state in real-time, thus play a critical role in promoting awareness and adoption of healthy lifestyles. Currently, wearable sensors mainly focus on tracking physical activities and vital signs and are unable to capture molecular-level information related to the body’s dynamic chemistry. Additionally, the invasive nature of the current blood-based sensing techniques makes them unsuitable for the daily monitoring of individuals across the general population. As an alternative, other biofluids, such as sweat and interstitial fluid, can be accessed noninvasively and analyzed to provide physiologically meaningful measures of biomarkers. To this end, chemical sensing interfaces are excellent candidates for performing wearable biomarker analysis in these biofluids. In this chapter, we discuss the underlying principles in the design and operation of wearable chemical biomarker sensors as well as the recent advances in the scientific field.
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