Abstract
Because of its unique physicochemical features, graphene and related nanoparticles are gradually becoming popular among various biomedical, diagnostic, drug delivery, and cosmeceutical product research groups. These electron-rich particles exert potent stress on cytocellular homeostasis, of which autophagy is one of the consequences. While the autophagic flow may lead to cell death and cytotoxicity, some studies established cytoprotective benefit of graphene compounds. The inductive extent of autophagy varies widely among the cell lines being exposed. Moreover, the size of the nanoparticles and the dose and treatment periods regulate the onset and magnitude of autophagy. In order to manipulate their safe theranostic application, a well-defined understanding of the underlying biochemical mechanism of graphene-medicated autophagy is warranted.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
