Abstract
The Layer-by-Layer (LbL) deposition procedure is a versatile technique, based on the sequential deposition of complementary molecular species on colloidal surfaces. The attachment of the LbL coating upon drug nanocore surfaces creates a multilayered thin core-shell nanocapsule. Owing to the electrostatic main driving force for multilayer LbL shell build-up, a wide variety of shell constituents can be used, ranging from synthetic to naturally derived polyelectrolytes, lipids, enzymes, viruses, colloids and other active compounds. These multilayered films allow the combination of several different materials at the nanoscale in a single unit, giving rise to novel and multifunctional architectures capable of performing numerous tasks required for systemic drug delivery. These features allow the possibility of drug protection and high drug loadings, together with drug release tuning capacities from the core by modulating the LbL coating permeability.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call