Abstract
Microbes have been present in our body since infancy and are known to play a vital role in metabolism, health as well as pathogenesis of diseases. Diabetes mellitus is one of the most prevalent metabolic disorders of the 21st century characterized by hyperglycemia and hyperinsulinemia. Symbiotics have recently emerged to have varied applications in the management of autoimmune, inflammatory, and allergic conditions and have also been reported to normalize disturbed glucose metabolism in diabetic patients by their ability to lower fasting glucose and insulin levels in preclinical and clinical studies. In this chapter, we have discussed the association between the body's microbiota and altered glucose metabolism, as well as the possible role of symbiotics in the modulation of the host's immune system for the treatment of diabetes mellitus.
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