Abstract
Similar to the peripheral skeletal muscles, the function of the respiratory skeletal muscles is affected by obesity. Obesity causes impairments to chest wall mechanics, reductions in lung volumes, and increased total respiratory system resistance. In addition, obesity-related chronic inflammation may also impair the contractile properties and force generating capacity of the respiratory muscles. These impairments and increased demands result in reductions in respiratory muscle strength and endurance. Reductions in respiratory muscle strength and endurance may contribute to the diminished cardiorespiratory fitness, abnormal ventilatory responses, and adverse symptoms often observed during exercise in obese individuals. Impaired respiratory muscle function and increased demands may also predispose obese individuals to pulmonary complications such as pneumonias, especially in perioperative state.
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