Abstract
In the current pandemic situation, the occurrence of co-infections and the development of drug resistance have posed a great challenge in the management of infectious diseases worldwide. Further, failure to control the spread of infectious diseases would endanger humanity. Recent discoveries and developments using nanotechnology have allowed us to tackle such situations by their application in diagnostics and treatment. In recent years, the use of nanomaterials in infectious diseases has gained wider attention. While understanding the physicochemical properties of nanomaterials, it is apparent that they differ from their bulk counterparts. Such differences may adversely affect the safety aspects of nanomaterials. There has been little information available on the safety aspects of nanomaterials used in infectious diseases. Thus, this chapter will focus on factors affecting nanomaterial's safety and ration approach for the selection of protocols to study biocompatibility and toxicity of nanomaterials. Considering the suitable selection of safety assessment protocols, the development of safer nanomaterials would be encouraged.
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