Abstract
Microfluidics is a field in continuous development, with applications that reflect its full benefits. In this chapter, a polydimethylsiloxane (PDMS)-based dual-channel microchip for electrophoresis is evaluated for the amperometric detection of different analytes of interest such as dopamine, catechol, p-aminophenol, and hydroquinone. A low relative standard deviation is achieved (less than 1.3%) for the migration time in measurements performed with the same microchip, which demonstrates the stability of the electroosmotic flow and the possibility of running multiple experiments in the same device. Moreover, adequate intermicrochip precision is also obtained. This, together with a rapid and simple manufacturing procedure, makes PDMS the material of choice in many applications.
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