Chapter 122 - Calibration Transfer Chemometrics, Part 1: Review of the Subject

Abstract

Calibration transfer involves multiple strategies and mathematical techniques for applying a single calibration database consisting of samples, reference data, and calibration equations to two or more instruments. The instruments used for initial calibration development and transfer may be of alike or meaningfully different optical designs. In this installment we are taking a broad overview of the chemometric and tactical strategies used for the calibration transfer process. However the emphasis for this chapter is on methods that modify the spectra or regression vectors to correct differences between instruments involved in the calibration transfer process. Chapters 114 and 116 on this subject review calibration transfer mathematics and approaches but do not address reference laboratory differences or maintenance of calibrations over time with changes in sample chemistry.