Abstract

The health-care sector has stringent needs for CyberInfrastructures (CIs) to improve both its patient-care capabilities and its potential for advanced clinical research. Large-scale projects reveal that economics, technology, science, and people need a careful balance to be successful. In this chapter, we detail our value-based methodology for architecting and implementing CIs for multiple projects in this field. We highlight the requirements and challenges presented by this field, the process for value-cost analysis, proper stakeholder involvement, and architecture evaluation to match a system’s timeline and budget. We also discuss lessons learned and typical CI aspects, including data ingestion and sharing, privacy and security, life-cycle management, rapid prototyping and user adoption, performance, and scalability, and their impact on project economics. We conclude with strategic factors for overall project success.

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