Abstract

The vitamin D receptor is present in beta cells and in other tissues involved in the pathogenesis of type 1 and 2 diabetes (i.e., immune system, liver, adipose tissue, and skeletal muscle). In vitro studies and studies in animal models suggest beneficial effects of supplemental vitamin D in diabetes, but in humans, only epidemiological data are available and prospective studies yield till now disappointing results. An overview of available evidence on the role of vitamin D in diabetes and glucose metabolism is given.

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