Abstract
Bioadhesive drug delivery systems have now been recognized as very promising systems for delivery of various therapeutic compounds. Bioadhesive drug delivery systems can be delivered through various routes like oral, nasal, ocular, and vaginal. The main components of bioadhesive drug delivery systems are bioadhesive polymers, which may be natural or synthetic in nature. The success of bioadhesive drug delivery systems depends upon bioadhesion bonding, which is influenced by polymer-based properties like chain length, cross linking, and presence of various functional groups. Mucosal covered organelles can be easily targeted by using bioadhesive systems in order to gain local or systemic effects. Efficiency of bioadhesive systems has prompted scientists to use more specific second-generation polymers having thiol, lectin and other adhesive functional groups rather than first-generation charged hydrophilic polymer networks to obtain therapeutic bioadhesion. Therefore, this chapter describes the role of various bioadhesive polymers for targeted delivery of various bioactive molecules.
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