Abstract

Pancreatic cancer ranks as the fourth cause of cancer-associated deaths in the West. It is an aggressive cancer with poor prognosis and a huge mortality rate. Current treatment modalities used for treating PC (surgery and chemoradiotherapy) have limited outcomes due to stroma-induced chemoresistance. These shortcomings stress the need for new therapeutic solutions with increased efficacy and cytotoxicity for PC. In recent years, nanotechnology has emerged as a promising solution for improving diagnosis, drug delivery, and treatment in many cancers including PC. In this chapter, we explore the various nanotechnologies developed to date, their chemical composition, pharmacological properties, and activity. We also discuss their potential as drug delivery solutions for PC.

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