Abstract
This chapter describes the approaches used in the assessment of risks associated with chemical contaminants and residues of plant protection products and veterinary drugs in food. Risk assessment consists of the interlinked stages of hazard identification, hazard characterization, exposure assessment, and risk characterization. Depending on the completeness of the toxicological database and the properties of a specific chemical, the aim is to set health-based guidance values, representing intakes judged to be without appreciable risk, or to identify margins of exposure between reference points associated with the dose–response curve and the estimated human dietary exposure. The impact of chemical risk on the process of risk management varies depending on the regulatory context.
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