Abstract

The silent killer or ovarian cancer (OC) is one of the major causes of cancer deaths among women in themodern age. In view of the therapeutic roles of platinum based chemotherapy among the ovarian cancerpatients, objective of this report was to assess the effects of the first round of chemotherapy among womenwith ovarian cancer. Here, the levels of the pleural markers for cancer bio markers, before and after thechemotherapy were tested among ovarian cancer patients. The biochemical indices may be of use indeciphering the relation between cancer relapse and platinum retrieval. The pleural analyses pre and postplatinum chemotherapy session demonstrated wide range of biochemical and protein marker changes amongovarian cancer patients. The various cancer antigens were variedly reduced post chemotherapy. Hence, it isproposed that biochemical markers in pleural liquid may serve as better indicators and early diagnostic toolsfor ovarian cancer.

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