Abstract
Ovarian cancer (OC) is one of the major causes of cancer deaths among women. Owing to the retrieval effects of platinum based chemotherapy among the ovarian cancer patients, objective of this report was to assess the effects of the first round of chemotherapy among women with ovarian cancer. Here, the levels of the pleural markers for the lipid profile and the cancer bio markers, before and after the cis-platin based chemotherapy were tested among ovarian cancer patients. The biochemical indices may be of use in deciphering the relation between cancer relapse and platinum retrieval. The pleural analyses pre and post platinum chemotherapy session demonstrated wide range of biochemical and protein marker changes among ovarian cancer patients. However, the pleural thickness and the pleural levels of the cancer biomarkers were not impressively reduced after the first cycle of chemotherapy. Hence, our data can be considered as a pavement for the discovery of further markers in the pleural liquid as well as a reliable monitor for chemotherapeutic response.
Published Version
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