Abstract

肝脏是人体代谢的主要器官,是凝血因子和纤溶物质合成的重要场所,对机体的凝血及纤溶系统的相互作用与动态平衡起主要调节作用.妊娠期新陈代谢旺盛,肝脏负担明显加重,一旦孕妇有产科诱发因素如妊娠合并病毒性肝炎,妊娠与肝炎相互影响,免疫反应过于激烈,多因素参与将肝脏损伤放大,短期内造成大量肝细胞坏死,肝功能严重受损.与非孕期相比,妊娠合并病毒性肝炎更易发展成重症肝炎,破坏机体凝血、纤溶系统之间的平衡,发生大出血,成为产妇死亡的主要原因[1-2].本研究旨在通过对39例妊娠合并慢性乙型肝炎患者的止、凝血和纤溶系统指标的检测,探讨其临床意义,为临床诊断、治疗及预后判断提供依据. 关键词:妊娠;肝炎,乙型;血液凝固因子;抗凝血酶类;纤溶

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