Cerebral CTPI and head and neck CTA feature of patients with transient cerebral ischemia and its correlation with clinic

Abstract

Objective To investigate the head and neck CTA findings and cerebral CTPI in patients with transient ischemic attack(TIA), and their relationship with frequency of TIA, duration and CTA detected responsible vessels. Methods 180 TIA patients were selected as the research subjects, the GE Lightspeed 64 spiral CT perfusion CT scan and CTA examination were taken, and the differences in CTPI parameters measurement, head and neck artery disease of patients were analyzed. To observe the correlation between CTPI perfusion abnormalities in patients with TIA seizure frequency, duration and NIHSS score. The CTPI perfusion abnormalities and consistency of CTA display of responsible vessels were analyzed. Results The positive rate of CTPI examination was 75.56%,that of CTA examination was 81.11%.The positive rate of patients(NIHSS≥4 points)with CTPI was 88.89%,which was higher than 66.67% in patients(NIHSS<4 points) with CTPI(χ2= 6.87,P<0.05).The positive rate of patients(seizures time≥10min)with CTPI TIA was 71.43%, which was higher than 45.45% of the patients(seizures time< 10min) with CTPI(χ2= 7.23,P< 0.05).The CTPI positive rate of patients with the TIA seizure frequency≥2 times/d was 83.33%, which was higher than 61.67% of patients with the seizure frequency<2 times/d(χ2= 5.48,P<0.05).The CTPI positive and CTA responsibility vascular consistent proportion was 73.33%,which was significantly higher than 26.67% of both inconsistent and negative(χ2= 19.43,P< 0.01). Conclusion The cerebral CTPI and head and neck CTA can response to TIA in patients with intracranial lesions accurately, consistency and clinical manifestations are very good, which have higher value in clinical application. Key words: Tomography, X-ray computed; Perfusion imaging; Cerebral angiography; Ischemic attack, transient; Stroke