Abstract
We describe a case-control study performed in Jiangsu, China, to evaluate risk factors for human infection with novel avian influenza A(H7N9) virus. Twenty-five cases and 93 controls matched by age, sex, and location were included in the study. Direct contact with poultry or birds in the two weeks before illness onset, chronic medical conditions (hypertension excluded), and environment-related exposures were significantly associated with A(H7N9) infection.
Highlights
All confirmed human cases of avian influenza A(H7N9) virus infection in Jiangsu Province were included in this study
We identified in the multivariate analysis three risk factors for human influenza A(H7N9) cases in Jiangsu, China, including direct contact with poultry or birds, environment-related exposures, and chronic medical conditions
Direct contact with poultry or birds was the most significant risk factor, which is consistent with previous studies on human cases of avian influenza A(H5N1) and A(H7N9) virus infection [2,4,5,6,7,8]
Summary
Case-control study of risk factors for human infection with influenza A(H7N9) virus in Jiangsu Province, China, 2013. We describe a case-control study performed in Jiangsu, China, to evaluate risk factors for human infection with novel avian influenza A(H7N9) virus. Direct contact with poultry or birds in the two weeks before illness onset, chronic medical conditions (hypertension excluded), and environment-related exposures were significantly associated with A(H7N9) infection Since it was discovered in February 2013, the emerging outbreak of human infections with a novel avian influenza A(H7N9) virus in China, has raised serious concerns for public health throughout the world [1]. We conducted a matched case-control study to identify potential risk factors for human influenza A(H7N9) cases in Jiangsu Province, one of the areas where the novel reassortant influenza A(H7N9) virus emerged earliest
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