Case Study] SARS-CoV-2 infection in a fully vaccinated case with newly diagnosed breast cancer: a case report

Anna Maria Vandone,Cinzia Ortega,Veronica Prati,Manuela Alessio,Giorgia Zucchini,Morena Ciceri

doi:10.32388/3sgegm

Abstract

BACKGROUND: the novel Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) was identified in 2019 inWuhan, China, and has not been previously identified in humans. SARS-CoV-2 disease resulted in a global pandemic, impacted on public health service and in major changes in the lifestyle and quality of life of population. CASE: we describe a 62-year-old woman with new diagnosis of breast cancer, infected with the SARS-CoV-2, within 14 days of the second dose of the BNT162b2 mRNA COVID-19 vaccine. CONCLUSION: in cancer population, timely vaccinations and maintenance of the maximum alert threshold, are necessary to prevent infection spreading.

Highlights

Coronavirus disease 2019 (COVID-19) has quickly spread worldwide, caused by SARS-CoV-2
Symptomatic infection developed after the second dose of the Pfizer BNT162b2 mRNA COVID-19 vaccine in the beginning of March 2021
Case Report We describe the case of a 62 years old woman with new diagnosis of breast cancer who, on 15 February 2021, received the first dose of the Pfizer BNT162b2 mRNA COVID-19 vaccine and the second one on 8 March 2021

Summary

Introduction

Coronavirus disease 2019 (COVID-19) has quickly spread worldwide, caused by SARS-CoV-2. The Pfizer-BioNTech COVID-19 vaccine was authorized by the European Commission and EMA on 21 December 2020[2] and was approved the following day by AIFA (Italian Medicines Agency) This case report describes a SARS-CoV-2 infection in a Italian female patient, with newly diagnosed breast cancer. Case Report We describe the case of a 62 years old woman with new diagnosis of breast cancer who, on 15 February 2021, received the first dose of the Pfizer BNT162b2 mRNA COVID-19 vaccine and the second one on 8 March 2021. After become aware of the close contact with a COVID-19 case, our patient underwent COVID-19 rapid antigen swab on 13 March 2021, five day after the second vaccine dose, obtaining a positive result. Because of SARS-CoV-2 infection, surgery for breast cancer was first postponed and later performed without sequelae on 14 April 2021 and than she started regular adjuvant treatment

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