Abstract
Aim: To assess the cardiovascular sympathetic activity in obese and normal weight young adults by recording Heart rate, QT interval and Blood pressure. Objectives: The study was undertaken to assess the effect of isometric handgrip exercise test on Heart rate, QT interval and Blood pressure (SBP & DBP) levels in obese and normal weight subjects. Results: Baseline recording showed statistically significant prolonged QT interval and higher blood pressure level in obese in comparison with normal weight group (p=0.001, p=0.001 respectively). The response to exercise test varied among the groups. The obese group showed significant decline in QT interval (p=0.002) and normal weight group showed significant rise in blood pressure (p=0.001). Conclusion: There is increased sympathetic activity, which is an important determinant of prolonged QT interval and elevated blood pressure in obesity. QT interval analysis is a cost-effective investigation in obese subjects who should receive a special medical attention.
Highlights
The maintenance of an adequate body weight is a major determinant of the survival and fitness of most of the higher organisms including human beings
The baseline mean ± S.D. value of QT interval, SBP and DBP were higher in obese group when compared to normal weight group, as shown in table II & III
The response to exercise test showed significant decline in QT interval in obese group when compared to normal weight group, as shown in table II
Summary
The maintenance of an adequate body weight is a major determinant of the survival and fitness of most of the higher organisms including human beings. There are mechanisms that tend to maintain energy intake and energy expenditure in balance. There is preponderant evidence for the existence of an adipose tissue mass which can control with signals that come in part from adipose tissue and that act on hypothalamic receptors with effectors in the autonomic nervous system[1]. Obesity is abnormal or excessive fat accumulation that represents a major risk factor for a number of cardiovascular diseases (CVD) such as, Hypertension, Coronary heart disease and Cardiac arrhythmias[2]. Obesity is a disorder of energy balance affecting a wide range of people.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
