Abstract
Objective To evaluate the curative effects of carbon nanoparticles on central lymphnode dissection in papillary thyroid carcinoma(PTC). Methods 72 PTC patients were randomly divided into two groups: carbon nanoparticle group(n=32)and the control group(n=32). Patients in the carbon nanoparticle group were injected with carbon nanoparticles during surgery. Patients in the control group had conventional surgery. The number of lymph nodes being dissected, lymph node metastasis, and the rate of hypoparathyroidism were compared between the two groups. Results The number of lymph nodes dissected in nanoparticle group(n=312)was much bigger than that in the control group(n=189)(P 0.01; χ2=1.048). Conclusions The lymphatic tracer technique may improve the number of lymph nodes dissected in central region of PTC and reduce parathyroid gland damage. Key words: Carbon nanoparticles; Papillary thyroid carcinoma; Lymph node metastasis; Parathyroid gland preservation
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